Self-Delivering Antisense Oligonucleotides (sdASO™)

AUM BioTech's premium product line requires no transfection reagents or special delivery vehicles. Simply add them to your cell culture or inject them in vivo and they'll do the rest.

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Self-Delivering ASOs

Why Choose Self-Delivering ASOs?

Effortless Delivery

No transfection reagents, electroporation, or viral vectors needed

Works in Any Cell Type

Effective in hard-to-transfect cells like primary cells, neurons, and immune cells

In Vivo Compatible

Can be used in animal models without special delivery formulations

Minimal Toxicity

No transfection reagent means less cellular stress and more reliable results

Transfection-Optimized ASOs (toASO™)

Transfection-Optimized ASOs (toASO™) product line offers the same high-quality gene silencing capability as AUM BioTech's self-delivering products, but specifically optimized for standard transfection protocols at a more budget-friendly price point. These products leverage our core AUMsilence platform and AI-driven design, with modifications tailored for excellent performance with common transfection methods. This makes them perfect for routine gene silencing in easy-to-transfect cell lines or high-throughput screening applications where cost-efficiency is a major consideration.

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Transfection-Optimized ASOs (toASO™)

When to Choose Transfection-Optimized ASOs (toASO™)

Budget Considerations

More cost-effective for large-scale experiments and screening applications

Standard Cell Lines

Ideal for commonly used cell lines that are easy to transfect (HEK293, HeLa, etc.)

High-Throughput Screening

Perfect for large gene panels and screening applications where cost per target matters

Academic Teaching

Great for educational labs and training where budget constraints exist

Need Help Choosing?

Our interactive product selection guide can help you find the perfect RNA silencing solution for your research.

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Self-Delivering Antisense Oligonucleotides (sdASO™)

Our premium product line that requires no transfection reagents or special delivery vehicles

AUM BioTech's self-delivering Antisense Oligonucleotides (sdASO™) represent a revolutionary approach to gene silencing. These products enter cells without any transfection reagents, electroporation, or viral vectors - simply add them to your cell culture or inject them in vivo and they'll do the rest. Our sdASO™ technology is powered by the AUMsilence platform, which combines advanced chemical modifications with AI-driven design to create highly effective gene silencing tools.

AUMsilence

Self-delivering ASOs for mRNA knockdown in virtually any cell type, without transfection reagents.

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AUMantagomir

Specialized ASOs for efficient inhibition of microRNAs in hard-to-transfect cells.

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AUMlnc

Designed for knockdown of long non-coding RNAs, including nuclear-retained transcripts.

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AUMsilence V+™

Specialized ASOs for targeting viral RNA genomes and transcripts with high precision.

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AUMblock

Steric blocking ASOs that bind to target RNAs and modulate function without RNA cleavage.

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AUMskip

Self-delivering ASOs designed to modify pre-mRNA splicing for exon skipping applications.

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Transfection-Optimized ASOs (toASO™)

Budget-friendly options for cost-effective research

Our Transfection-Optimized ASOs (toASO™) product line offers the same high-quality gene silencing capability as our self-delivering products, but specifically optimized for standard transfection protocols at a more budget-friendly price point. These products leverage our core AUMsilence platform and AI-driven design, with modifications tailored for excellent performance with common transfection methods. This makes them perfect for routine gene silencing in easy-to-transfect cell lines or high-throughput screening applications where cost-efficiency is a major consideration.