RNA Silencing Products

AUM BioTech's self-delivering Antisense Oligonucleotides (sdASO™) represent a revolutionary approach to gene silencing. These products enter cells without any transfection reagents, electroporation, or viral vectors - simply add them to your cell culture or inject them in vivo and they'll do the rest. Our sdASO™ technology is powered by the AUMsilence platform, which combines advanced chemical modifications with AI-driven design to create highly effective gene silencing tools.

Our Transfection-Optimized ASOs (toASO™) product line offers the same high-quality gene silencing capability as our self-delivering products, but specifically optimized for standard transfection protocols at a more budget-friendly price point. These products leverage our core AUMsilence platform and AI-driven design, with modifications tailored for excellent performance with common transfection methods. This makes them perfect for routine gene silencing in easy-to-transfect cell lines or high-throughput screening applications where cost-efficiency is a major consideration.

AUM BioTech's Enhanced siRNA Technology represents our chemically enhanced small interfering RNA molecules designed for researchers who prefer the familiar RNAi pathway for gene silencing. Built with proprietary chemical modifications, these 21-23 nucleotide duplexes offer superior stability, potency, and specificity compared to unmodified siRNAs. Our enhanced siRNAs incorporate strategic chemical modifications that improve nuclease resistance, reduce immune activation, and enhance guide strand selection – all while maintaining compatibility with standard transfection protocols you already use in your lab.